In a mixing bowl, combine mayonnaise, sour cream, chipotle peppers in adobo sauce, garlic powder, onion powder, lime juice, salt, and pepper.
Use a hand blender or whisk to blend the ingredients until smooth and creamy. Adjust the seasoning to taste, adding more lime juice or chipotle peppers if you prefer extra heat.
Cover the bowl and refrigerate for at least 30 minutes to allow the flavors to meld together.
Serve as a dipping sauce, drizzle over tacos, or use as a topping for grilled chicken or burgers.
Notes
Feel free to adjust the spice level by adding more chipotle peppers or cayenne pepper. For a lighter option, replace the mayo with Greek yogurt.